![]() String layout::getOpenFilename( string filter="", string path="")Ī file open dialog is shown. 1 is returned in the case the Cancel button was pressed. Returns: the layer number set by the user. This string will be displayed inside the window The execution of this macro stopped until the termination of the new started macro. Int layout::executeMacro( string filename)Īnother macro is executed. The design rule checker is accessible via this class. This class is the main class of the drawing. The current design will be removed and an empty design is shown like after the program start. The selected file will be imported.(= add to the existing file) The boolean utilities are accessible via this class pointer. The barcode utilities are accessible via this class pointer. The background utilities are accessible via this class pointer. MacroToolButtons will not stored with shut-down. If the given file does not exist, the default macro icon is used. iconfilename points to the file for the icon of the new button. macroName specifies the name of the macro to be executed. If this toolbar does not exist, it will be created. The button will be added to the toolbar 'Macros'. Void layout::addMacroToolButton( string macroName, string parameter, string iconfilename)Īdd a new button to the toolbars. L=Project.new_layout() # open new instance of layout class for Ruby l=project.newLayout() # open new instance of layout class for Python A new layout object had to be created via the project class. In LayoutScript the keyword layout does not exists. See also: MacroClassBackgroundModule, MacroClassBarcodeModule, MacroClassBooleanHandler, MacroClassDrawingField, MacroClassDrc, MacroClassView3dModule A direct access of the drawing is possible via the member drawing to an object of the class drawingField.įurther modules to modify the design data are available with the pointers backgroundTool, barcodeTool, booleanTool, drcTool and netlistTool. Most methods of this call require a user dialog. Layout->filename="/var/layouts/samples1.gds" It is directly accessible via the classname "layout". This class is the main widget of the window from which the macro was executed. showMessage(string caption,string label).setShortcut(string function,string key).getText(string caption,string label,string value="").getSize(QString caption,QString label, int value=1).getOpenFilename(string filter="", string path="").getItem(string caption,string label,stringList values).getInteger(string caption,string label, int value=0).getDouble(string caption,string label,double value=0, int digits=1).addMacroToolButton(string macroName,string parameter,string iconfilename).Our findings show that Mcl-1 is an essential regulator of stem cell self-renewal in humans and therefore represents an axis for therapeutic interventions. Moreover, knockdown of Mcl-1 in ontogenetically primitive human pluripotent stem cells resulted in almost complete ablation of stem cell self-renewal function. Short hairpin RNA-knockdown of Mcl-1 in human cord blood cells did not affect survival in the HSC or hematopoietic progenitor cell fractions in vitro but specifically reduced the in vivo self-renewal function of human HSCs. Subsequent protein expression studies showed that, among the Bcl-2 family members, only Mcl-1 was up-regulated exclusively in the human HSC fraction on in vivo regeneration of hematopoiesis. In vivo pharmacologic targeting of the Bcl-2 family members in human hematopoietic stem cells (HSCs) and human leukemic stem cells reduced stem cell regenerative and self-renewal function. We report a role for the Bcl-2 family member myeloid cell leukemia-1 (Mcl-1) as an indispensable regulator of self-renewal in human stem cells and show that a functional dependence on Mcl-1 defines the human stem cell hierarchy. The molecular basis for the unique proliferative and self-renewal properties that hierarchically distinguish human stem cells from progenitors and terminally differentiated cells remains largely unknown.
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